Medical Research
Pain, Inflammation and Medicinal Grade Essential Oils
Topical dermal application of essential oils attenuates the severity of adjuvant arthritis in Lewis rats
www.ncbi.nlm.nih.gov/pmc/articles/PMC3168704/
"This study was aimed at examining the effect of an ointment containing essential oils (EO) on the severity of adjuvant arthritis (AA), an experimental model of human rheumatoid arthritis (RA), in Lewis rats and to define the underlying mechanisms.
Several reports suggest the efficacy of topical application of medicinal products for different inflammatory conditions. Singh et al, reported the anti-inflammatory activity of Boswellic acids (Frankincense) through topical application using different models of acute and chronic inflammation...
Essential oils are natural plant products that possess anti-oxidant, anti-bacterial, anti-fungal and anti-inflammatory properties (Agarwal and Rangari, 2003; Burt, 2004; Kordali et al., 2005). Essential oils from ginger, orange and black cumin have been shown to hold promise for the relief of symptoms of arthritis (Osborn et al., 2001; Tekeoglu et al., 2007; Yip and Tam, 2008). Essential oils and their components are rapidly absorbed through the skin and are detectable in plasma after topical application (Jaeger, 1992). Therefore, topical dermal delivery of EO represents an effective method to directly deliver a natural, anti-inflammatory agent to the site of inflammation."
Frankincense and myrrh suppress inflammation via regulation of the metabolic profiling and the MAPK signaling pathway
www.ncbi.nlm.nih.gov/pmc/articles/PMC4556964/
"Frankincense and myrrh are highly effective in treatment of inflammatary diseases, but lacking of the therapy mechanisms. We undertook this stuty to evaluate the effects on Adjuvant-induced Arthritis (AIA) rats and to explore the underlying mechanisms by analyzing the metabolic profiling and signaling pathway evaluated by expression of inflammatory cytokines, c-jun and c-fos and corresponding phosphorylation levels. The results stated the elevated expression levels of TNFα, PGE2, IL-2, NO, and MDA in serum and swelling paw of AIA rats were significantly decreased after treatment, which exerted more remarkable inhibitive effects of combined therapy.
Ruxiang (Frankincense) is dried gum resin of Boswellia carterii or one of 43 species in the genus Boswellia of the family Burseraceae. It has been commonly used to reduce swelling and alleviate the pain of inflammatory diseases or tumors31,32, and to invigorate the circulation of blood in China and as an antiarthritic in Ayuredic medicine in India for thousands of years31. Moreover, it is also used as dietary supplements for patients with arthritis or other inflammation and pain related disorders in USA33. Previous studies in vitro have shown that the boswellic acids isolated from Frankincense exhibited potential immunomodulatory effects34,35.
Myrrh, as a traditional natural medicine, is an aromatic gum resin, which was the plant stem resinous exudate of Commiphora myrrha (Nees) Engl. (Burseraceae) and various other different species of Commiphora family. It has many medicinal powers and has been used widely in clinic for treatment of pain and inflammatory diseases, such as stomach complaints, skin infections, ache, dysmenorrhea, chest ailments, and so on, in India, China, Rome, and Greece36,37,38. Especially, the myrrh was a common analgesic and has been used to clean wounds and sores for more than 2000 years, until the European discovered the morphine. Pharmacological studies also have showed that myrrh possesses multiple activities, including anti-inflammatory, cytotoxic, anesthetic, and antimicrobial effects39.
In China, Frankincense and Myrrh are often used together on clinic in order to obtain a synergistic effect for relieving pain and activating blood circulation, and especially to treat inflammatory diseases (e.g., RA). However, the evaluation of the effects and mechanisms are lack."
Essential Oils for Pain and Inflammation
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The top ten essential oils are
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Why doTERRA?
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Anti-inflammatory Foods
Turmeric, ginger, garlic, cinnamon and cayenne are very beneficial spices to add to your every day cooking.
Living with chronic pain and inflammation is not easy but you can manage them if your adopt an anti-inflammatory diet.
Living with chronic pain and inflammation is not easy but you can manage them if your adopt an anti-inflammatory diet.
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